Skin signals offer vital clues to serious diseases, expediting treatment. “Persistent and severe rashes demand medical attention,” warns experts. Conditions like Addison’s disease can trigger sudden discoloration. Deadly infections like Lyell’s syndrome show as severe rashes, notably in adults with chickenpox. Chronic edema may point to hypothyroidism, exhibiting dry skin and hair loss. “New moles or changes warrant a doctor’s visit,” advises specialists. Acne, often from oily skin, needs careful management. “Flaking skin with severe symptoms could indicate a life-threatening condition,” cautions experts. Excessive sweating might signal Graves’ disease. Immediate medical attention is crucial upon noticing these signs.